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Quetiapine versus risperidone in elderly patients with behavioural and psychological symptoms of dementia: Efficacy, safety and cognitive function

Objective: In this study we directly compared the efficacy and tolerability of the atypical antipsychotics quetiapine and risperidone in elderly patients with dementia and symptoms of disturbed perception, thought content, mood...

Risk of Diabetic Ketoacidosis after Exposure to Risperidone or Olanzapine

Background: Atypical antipsychotics have been associated with metabolic abnormalities including impaired glucose metabolism, exacerbation of existing diabetes mellitus and new-onset type 2 diabetes. Not all atypical antipsychotic...

Effectiveness of Olanzapine, Quetiapine, and Risperidone in Patients With Chronic Schizophrenia After Discontinuing Perphenazine: A CATIE Study

OBJECTIVE: The relative effectiveness of newly started antipsychotic drugs for individuals with schizophrenia may depend on multiple factors, including each patient’s previous treatment response and the reason for a new...

Confounding by Indication and the Risk of Hyperlipidemia in Observational Studies of Antipsychotics

Using an elegant case-control design, Mark Olfson, M.D., M.P.H., et al. have reported a somewhat weak but significant association between treatment with clozapine, risperidone, olanzapine, quetiapine, or ziprasidone, and the risk...

How to Choose Antipsychotic Medication

Over the past several years a bevy on new antipsychotic pharmaceutical options has come on the market for treatment of schizophrenia. A new study provides insight for comparing treatment options when an older, first generation...

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